Clinico Pathological Study of Ovarian Tumors and its Relative Frequency in Women of Different Age Groups
Introduction: Ovaries are common site for both benign and malignant tumors, the ovarian cancer being one of the major causes of suffering in women globally. They are seen in all age groups depending on their type. These tumors are responsible for major part of morbidity and mortality due to multitude of factors including socio-economic conditions, cultural issues and personal negligence. In order to diagnose these tumors just clinical and radiological findings are not sufficient; a thorough histopathological examination is the gold standard for ultimate diagnosis and management of patient.
Objectives: The main objective of this study is to evaluate clinic pathological features of benign and malignant ovarian tumors.
Material and Methods: This is a retrospective study of ovarian specimens that were received in the Histopathology section of Institute of Kidney Diseases (IKD) over a period 5 years from July 2014 till July 2019 from all the Gynecology Units of Hayatabad Medical Complex.
Results: A total of 229 cases of ovarian tumors were included in this study with age range from 1 year to 80 years.Maximum number of both benign and malignant tumors was seen in the age groups from 21-40years. Most common presentation was abdominal pain followed by abnormal uterine bleeding. 78.6% were married,64.19% cases were premenopausal, and 61% were nulliparous.63.31% cases were benign, 2.19% were borderline while 34.49% were malignant. Most common benign tumor was dermoid cysts followed by serous and mucinous cystadenoma. The most common malignant tumor was papillary serous cystadenocarcinoma.
Conclusions: The majority of ovarian tumors in our study were benign among which dermoid cyst was most frequent. Among malignant tumors the most frequent was papillary serous cystadenocarcinoma.Most common risk factors associated with ovarian tumors were nulli parity, menstrual irregularities, previous surgeries and a family history of ovarian/breast cancers.