Juvenile Myelomonocytic Leukemia
Keywords:
Juvenile Myelomonocytic Leukaemia, Hematopoietic Stem Cell TransplantationAbstract
Juvenile Myelomonocytic Leukemia (JMML), which comes under the WHO category of Myelodysplastic/
Myeloproliferative Neoplasms, is a rare aggressive hematological malignancy of early childhood caused by
excessive proliferation of cells of monocytic and granulocytic lineages. The peripheral blood shows leukocytosis,
thrombocytopenia and anemia. The majority of patients present with infection. Hematopoietic Stem Cell
Transplantation (HSCT) is the best treatment option available. Here we present a case of a one year old female
child who presented with complaints of fever, cough and progressive pallor for the last six months and
abdominal distention associated with vomiting, diarrhea and sub-conjunctival hemorrhages for past 2 months.
The fever did not respond to medication. She developed sepsis and intracranial bleed and expired on the 10th day
of hospitalization
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Copyright (c) 2018 Amna Imtiaz, Lubna Naseem, Sundas Ali
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