Myelodysplastic Syndrome in Childhood
Keywords:
Childhood Myelodysplastic syndromes, cytopenias, dysplasia.Abstract
Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal stem cell disorders,
characterized by cytopenias due to impaired blood cell production and hyper cellular and dysplastic
bone marrow. The significance of MDS lies in the increased incidence of leukemic transformation.
Many morphologic, immunophenotypic and genetic features observed in MDS in adults are also seen
in childhood form of disease, but significant differences are reported especially in patients who do not
have increased blasts in peripheral blood or bone marrow. Here we present a case of six years female,
resident of Yemen, who presented to us with suspicion of aplastic anemia but later she was diagnosed
as a case of MDS.
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Copyright (c) 2018 Hina Bilal, Lubna Naseem, Nazia Siddiqui
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