Diagnostic Utility of Bone Marrow Examination in Chronic Liver Disease Patients Referred For Evaluation of Hematological Derangements
Keywords:
Chronic liver disease, HCV, pancytopenia, cytopeniasAbstract
Objective: To see the diagnostic utility of bone marrow examination in patients of chronic liver disease referred
for evaluation of hematological derangements.
Material and methods: The study was conducted from July 2009 to July 2011 at the Department of Pathology,
Pakistan Institute of Medical Sciences (P.I.M.S), Islamabad. A total of 75 diagnosed cases of Hepatitis C induced
chronic liver disease, referred from different departments of PIMS with various indications for bone marrow
examination were included in the study. All these cases were qualitative PCR-positive for HCV-RNA. Patient who
had already received or were on anti -viral therapy were excluded. Routine blood cell counts were done and later
all the patients were subjected to bone marrow examination. Data was entered on SPSS version 16 and statistically
analyzed.
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