Dengue a Worldwide Threat: Need to be Ceased with Systematic Scientific Measures to Stop its Fast Desolation Throughout the World

  • Muhammad Ibrahim Department of Biosciences, COMSATS University Islamabad, Pakistan
  • Syeda Safia Hashmi Department of Chemistry, Islamia College University Peshawar, Pakistan
  • Syed Salman Department of Chemistry and Biology “A. Zambelli” University of Salerno, Italy
  • Syeda Jawariya Hashmi Department of Botany Frontier College for Women Peshawar, Pakistan
  • Syeda Asma Taskeen Department of Botany, Islamia College University Peshawar, Pakistan
  • Muskan Shabbir Department of Pathology University of Veterinary and Animal sciences (UVAS), Lahore Pakistan
  • Immad Khan Institute of Chemical Sciences, University of Peshawar, Pakistan
  • Muhammad Shabbir Ahmad Institute of Chemical Sciences, University of Peshawar, Pakistan
Keywords: Dengue virus, Aedes aegypti, Dengue hemorrhagic fever, vaccine


Dengue virus belongs to family Flaviviridae and genus Flavivirus, transmitted primarily in a cycle through human beings and mosquito vector. The rate of incidence of dengue fever epidemics has reached to the highest, since past few years. Over a geologically expanding area, the level of hyperendemic transmission has been established. The person with sequential dengue infection is also victim of dengue hemorrhagic fever (DHF) which is the most sever disease. The rate of incidence of DHF and the possibility of sequential infections, has increased intensely, first of all in Asian countries and currently in America. The wide spreading of mosquito Aedesaegypti is even more alarming. As a consequence of insufficiency of antiviral drugs and potential vaccine, a large number of individuals are infected with severe dengue virus every year which causes huge death cases.

Conclusion: Presently, to prevent epidemics, controlling the dengue mosquito is the only available method. New investigation fordiscovery of potential vaccine, evaluation of vector control tools and approaches are desirable