Trends of Bacterial Pathogens and their Antimicrobial Susceptibility in Ocular Cultures

Authors

  • Mehwish Sajjad Department of Pathology, Dow University of Health Sciences
  • Maryam Shahid Dow University Hospital (Ojha Campus)
  • Zainullah . Dow University Hospital (Ojha Campus)
  • Bashir Ahmad Dow University Hospital (Ojha Campus)
  • Hussain Ahmad Dow University Hospital (Ojha Campus)
  • Rimal Rashid Dow University Hospital (Ojha Campus)

Keywords:

Ocular infection, antibiotic resistance, streptococcus pneumonia, staphylococcus aureus

Abstract

Background: Eye infections caused by bacteria are a serious public health problem. These diseases, if not properly treated, can cause blindness and impaired vision. The study is designed to evaluate the bacterial etiologies and antimicrobial resistance profiles of the main pathogens involved in eye infections.

Objectives: To isolate different pathogens from ocular culture and evaluate the antibiotic susceptibility pattern of these organisms

Materials and Method: This was a retrospective study in which we retrieved the data of ocular cultures in Dow Diagnostic Reference and Research Laboratory, Dow University of Health Sciences from the period of 1stJanuary 2019 to 31stDecember 2021. All details including bacterial etiologies and antimicrobial susceptibility pattern were noted from the retrospective data.

Results: During the study period, 44 patients were recruited who were requested by a physician for ocular cultures from the period of 1stJanuary 2019 to 31stDecember 2021.  Most common bacterial isolate found is Streptococcus pneumonia followed by Staphylococcus aureus and Pseudomonas aeruginosa. In this study all bacterial isolate exhibited 100% susceptibility against chloramphenicol except Streptococcus pneumonia which is 94% susceptible. Streptococcus pneumonia had 100% resistance against Trimethoprim- sulfamethoxazole whereas 100% susceptibility against clarithromycin, linezolid and levofloxacin.

Conclusion: Inference of study is that Coagulase Negative Staphylococcus was resistant to penicillin.  This has a significant effect on the options of empirical management of ocular infections.

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Published

2023-07-31

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Section

Original article

How to Cite

1.
Sajjad M. Trends of Bacterial Pathogens and their Antimicrobial Susceptibility in Ocular Cultures. Int J Pathol [Internet]. 2023 Jul. 31 [cited 2024 Jun. 20];:59. Available from: https://jpathology.com/index.php/OJS/article/view/834

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