Posterior Mediastinal Ancient Schwannoma Mimicking a Cyst

  • Kanwal Zahra Department of Pathology, Pakistan Institute of Medical Sciences, Islamabad
  • Ahmareen Khalid Department of Pathology, Pakistan Institute of Medical Sciences, Islamabad
  • Tayyaba Ali Department of Pathology, Pakistan Institute of Medical Sciences, Islamabad
  • Maria Omair Department of Pathology, Pakistan Institute of Medical Sciences, Islamabad
  • Gul- Afshan Department of Pathology, Pakistan Institute of Medical Sciences, Islamabad
  • Shaista Khursheed Department of Pathology, Pakistan Institute of Medical Sciences, Islamabad
Keywords: Posterior mediastinum,, Schwannoma, Peripheral nerves

Abstract

Background: Several types of neurogenic tumors can occur in mediastinum and commonly present as posterior
mediastinal mass lesions. Generally they are categorized in to those arising from peripheral nerves or
sympathetic ganglia. Schwannoma is the most common neurogenic tumor of this area. Generally they are
presented as solid encapsulated lesions and are difficult to miss on radiology. Rarely they can be large enough to
undergo cystic degeneration and cause confusion with other cystic mass lesions of the area. Large masses can
also cause pressure symptoms and leads to respiratory compromise.
Conclusion: Posterior mediastinal schwannomas though usually are benign and asymptomatic but can prove
fatal if attain a very large size. It should always be included in the differential diagnosis of posterior mediastinal
large cystic masses. Degenerative nuclear atypia associated with ancient schwannoma should not be confused
with malignancy. Patient can lead a symptom free life after surgical resection of these tumors.

Published
2018-11-21
How to Cite
Zahra, K., Khalid, A., Ali, T., Omair, M., Afshan, G.-, & Khursheed, S. (2018). Posterior Mediastinal Ancient Schwannoma Mimicking a Cyst. International Journal of Pathology, 122-125. Retrieved from https://jpathology.com/index.php/OJS/article/view/250

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