Multidrug Resistant Escherichia coli and Klebsiella pneumoniae Causing Urinary tract Infection in Pregnant Women
Keywords:
MDR, E. coli, K. pneumoniae, UTI, pregnancyAbstract
Objective: Identify the multidrug resistant Escherichia coli and Klebsiella pneumoniae occurring in pregnant
women with urinary tract infection.
Materials and Methods: A total of 200 clean catch midstream urine specimens (MSU) were collected
from pregnant women in a sterile container. Specimens were then inoculated on Blood agar, Mac-
Conkey agar and cysteine lactose electrolyte deficient (CLED) agar medium. Uropathogens were identified
by using battery of tests. Antimicrobial susceptibility was determined by Kirby Bauer disc diffusion
method as per Clinical and Laboratory Standard Institute (CLSI) guideline.
Results: E. coli constituted 39.70% of bacterial population followed by K. pneumonia 20.58%. Antimicrobial
tests, of isolated strains showed 92.68% sensitivity to imipenem, 87.8% to piperacillin/ tazobactam
while 100% resistance to ampicillin.
Conclusion: E. coli remained the most common cause of UTI followed by K. pneumonia. Imepenem
showed high sensitivity to UTI as compared to piperacillin/ tazobactam in our set up.
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Copyright (c) 2018 Naveen Qadeer, Muhammad Asif Durrani, Syed Manzoor Iqbal
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