Proteomics in neurodegenerative disease

unlocking hidden therapeutic targets

Authors

DOI:

https://doi.org/10.59736/IJP.23.03.985

Keywords:

Biomarkers, Neurovegetative Disease, Proteomics, Therapeutic Targets

Abstract

Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS lack effective disease-modifying therapies due to complex, heterogeneous mechanisms. Proteomics provides a powerful platform to map protein networks, post-translational modifications, and signaling pathways directly involved in pathology. Recent advances in mass spectrometry and bioinformatics enable biomarker discovery and identification of novel therapeutic targets beyond conventional proteins. Integrated with other “omics” approaches, proteomics supports systems biology and precision medicine strategies. Despite challenges in tissue availability, data complexity, and validation, proteomics is rapidly advancing as a frontier in neurodegeneration research, offering promise for earlier diagnosis and innovative therapeutic interventions.

Author Biography

  • Sarwat Jahan, Northwest School of Medicine, Peshawar Pakistan

    Associate Professor Pharmacology & Therapeutics

References

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Published

2025-09-29

Issue

Section

Editorial

How to Cite

1.
Jahan S. Proteomics in neurodegenerative disease: unlocking hidden therapeutic targets. Int J Pathol [Internet]. 2025 Sep. 29 [cited 2025 Oct. 8];23(3):114-5. Available from: https://jpathology.com/index.php/OJS/article/view/985

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