Quantitative computed tomography is a novel diagnostic tool for early scrutiny of osteopenia and/or osteoporosis

Authors

  • Rizwan Uppal Department of Research and Development, Islamabad Diagnostic Center (IDC), Islamabad
  • Umar Saeed Department of Research and Development, Islamabad Diagnostic Center (IDC), Islamabad
  • Muhammad Rehan Uppal Department of Research and Development, Islamabad Diagnostic Center (IDC), Islamabad
  • Aftab Ahmad Khan Department of Research and Development, Islamabad Diagnostic Center (IDC), Islamabad
  • Zahra Zahid Piracha International Center of Medical Sciences Research (ICMSR), Islamabad

Keywords:

Quantitative Computed Tomography, Dual-Energy X-ray Absorptiometry, Osteoporosis

Abstract

Background: Osteoporosis is a significant public health concern, particularly affecting women. Accurate diagnosis of osteoporosis is crucial for early intervention. This study aimed to evaluate the effectiveness of Quantitative Computed Tomography (QCT) and Dual-Energy X-ray Absorptiometry (DXA) scans in individuals suspected of having osteoporosis.

Methods: A cross-sectional study was conducted at the Islamabad Diagnostic Centre from June 2022 to June 2023. Participants suspected of having osteoporosis were recruited and underwent QCT and DXA scans. QCT evaluated inner trabecular bone, while DXA assessed bone mineral density (BMD). Diagnostic findings were compared.

Results: Of the participants, 89.3% had lower average QCT-T scores than DXA-T scores. QCT detected osteopenia in 96.6% and osteoporosis in 57.1% of subjects, while DXA identified osteopenia in 65% and osteoporosis in 10.7%. QCT demonstrated early detection potential, particularly for osteoporosis.

Conclusion: QCT is a reliable tool for early diagnosis of osteopenia and osteoporosis, as it accurately assesses inner spongy trabecular bone. It offers advantages over DXA, including cost-effectiveness in low- and middle-income countries. Global health strategies should prioritize osteoporosis assessment, considering the findings of this study

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Published

2023-10-23

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Section

Original article

How to Cite

1.
Uppal R. Quantitative computed tomography is a novel diagnostic tool for early scrutiny of osteopenia and/or osteoporosis. Int J Pathol [Internet]. 2023 Oct. 23 [cited 2024 Jun. 20];21(3):96. Available from: https://jpathology.com/index.php/OJS/article/view/851