Vaginal Amelanotic Malignant Melanoma in a Young Patient

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

Vaginal Amelanotic Malignant Melanoma in a Young Patient

Madiha Sajjad and Samina Iltaf
Department of Histopathology, Islamic International Medical College, Rawalpindi.

Malignant melanomas of female genital tract are rare malignancies occuring in older individuals. Amelanotic melanomas are consequently rarer as they make up a small fraction of vaginal melanomas. Amelanotic malignant melanoma a unique variant of melanoma is difficult to differentiate from other epithelial and nonepithelial
malignancies due to absence of melanin pigmentation. This report describes a case of vaginal amelanotic melanoma occuring in a young patient, which was confirmed on immunohistochemistry using S-100, HMB-45 and Melan A.


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