Sea Blue Histiocytosis Secondary to Niemann Pick Disease

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Sea Blue Histiocytosis Secondary to Niemann Pick Disease

Mobina Ahsan Dodhy, Wardah Aslam, Amna Nazir, Masooma Shaheen,
Maryam Habib, Humaira Zafar
Department of Pathology, Benazir Bhutto Hospital, Rawalpindi

Abstract: Sea blue histiocytosis is a rare disorder, characterized by the presence of atypical macrophages (sea
blue histiocytes) in the bonemarrow detectable by May-Giemsa staining. We report a case of a 3 years old female
,whose bone marrow examination revealed numerous sea blue histiocytes and Niemann-Pick cells (storage cells)
.Niemann-Pick disease is the most common cause of secondary sea-blue histiocytosis.
Keywords: Sea-blue-histiocytosis, Niemann Pick disease


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