Fine Needle Aspiration Cytology of Bone Marrow

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

Fine Needle Aspiration Cytology of Bone Marrow

Malik Mahmood Ahmed and Anwar Ul Haque

Department of Pathology, Azad Jammu & Kashmir Medical College, Muzaffarabad



Background: Fine needle is defined as a needle with a diameter of less than 0.21 mm (21 gauge). Fine Needle Aspiration Cytology is a time tested, reliable technique for diagnosis of lesions of various organs. However this has not been yet tested in bone marrow.

Objective: Assess the feasibility of Fine Needle Aspiration Cytology in bone marrow.

Patients and Methods

Setting: Department of Pathology, Azad Jammu and Kashmir Medical College / Sheikh Zayed Bin Khalifa hospital Muzaffarabad

Subjects: Fine Needle Aspiration Biopsy was first performed on 30 patients referred for conventional bone marrow aspiration examination to our department with their consent. Procedure was performed using 22 gauge needle and 10 cc syringe.

Results: The Fine Needle Aspirate was quiet adequate in 27 cases (90%) revealing normal abnormal hematopoietic cells as well as non-hematopoietic elements.

Conclusion: In many cases, Fine Needle Aspiration Cytology of bone marrow has great potential of replacing conventional thicker bone marrow aspiration needle which is much more painful and uncomfortable.

Keywords: Bone marrow aspiration, bone marrow biopsy, Fine Needle Aspiration Cytology, FNAC, Hematological disorders


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