R. Hafeez*, A.S. Chughtai.
* Consultant Microbiologist, Chughtais Lab, 8, Jail Road, Lahore.
Cryptococcus neoformans is a saprophytic encapsulated yeast with a worldwide distribution in soil contaminated usually with avian excreta, mostly from pigeons(1). Infection is acquired by inhalation of the organism and could be asymptomatic and limited to the lungs, especially in the immunocompetent host.(2) Haematogenous dissemination, especially to the meninges, and fatal outcome occurs in patients with other disorders, particularly malignancy, diabetes mellitus, treatment with corticosteroids and infection with human immunodeficiency virus.(3) Although there is a marked increase in the incidence of cryptococcosis around the world, due to its association with AIDS, reports concerning this infection from our region are rare.(4,5,6)
Here we report a case of C. neoformans meningitis and present an update on the pertinent literature, especially in relation to non AIDS versus AIDS patients.