Mudassira and Anwar Ul Haque
Department of Pathology, Pakistan Institute of Medical Sciences, Islamabad.
We report a case of diffuse small blue cell tumor of liver diagnosed on fine needle aspiration cytology (FNAC) in a 10 month old boy. He presented with chronic diarrhea and low-grade fever. On Physical and ultrasound examinations he had diffuse hepatomegally. However no discrete mass was present. The FNAC of the liver showed numerous atypical small blue cells ,some of which were forming cords and trabeculae. A few macrophages with cytoplasmic vacuoles mimicking Neiman Pick cells were also seen. There was also evidence of extramedullary hematopoiesis. The Bone marrow examination revealed hyperplastic erythrpoitic activity with few cells resembling Neiman pick cells.