Acute Monocytic Leukaemia with Reactive Plasmacytosis

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

Acute Monocytic Leukaemia with Reactive Plasmacytosis

Mobina Ahsan Dodhy, Maryam Habib, Masooma Shaheen, Masood Abassi
Department of Pathology, Benazir Bhutto Hospital, Rawalpindi


An increased plasma cell count in bone marrow of patients of Acute Myeloid Leukaemia occurs in a subgroup of patients. There are very few case reports which document an increase in number of plasma cells at time of initial diagnosis of Acute Myeloid Leukaemia. Here we present a case of 45- year old- male diagnosed as Acute Monocytic Leukaemia with Reactive Plasmacytosis, which posed much difficulty in diagnosis. The production of paracrine interleukin- 6 by leukaemic blast cells is thought to cause this reactive increase in plasma cells.
Keywords: Acute myeloid leukaemia, Reactive plasmacytosis, Paracrine interleukin-6.


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