Value of Touch Preparation Cytology in Intraoperative Consultation Diagnosis of Astrocytomas

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

Value of Touch Preparation Cytology in Intraoperative Consultation Diagnosis of Astrocytomas

Humaira Nasir and Anwar Ul Haque
Department of Pathology, Pakistan Institute of Medical Sciences, Islamabad.

Intra-operative diagnosis of brain tumours routinely employs frozen sections. The frozen section however has several
limitations and induces serious freezing artefacts. We carried out a prospective study on 40 cases of astrocytomas utilizing touch preparation cytology. The smears were quite cellular with crisp cellular details. There was 98.4% sensitivity and 90% specificity. We found touch preparation cytology highly reliable mode of intra-operative diagnosis in astrocytomas.
Keywords: Gliomas, Astrocytomas, Touch Preparation Cytology, Frozen Section.

         

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