Synchronous Development of Gastrointestinal Stromal Tumor and Arteriovenous Malformation in the Jejunum

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

Synchronous Development of Gastrointestinal Stromal Tumor and Arteriovenous Malformation in the Jejunum

Saira Javeed , Ruqayya Ishaq, Ahmareen Khalid and Ashok Kumar Tanwai
Pathology Department, PIMS, SZABMU

Abstract
This case report is about synchronous development of gastrointestinal stromal tumors (GISTs) with AV malformations (AVMs). A 23-year-old pale woman presented with melana and anemia. Abdominal computed tomography Non Enhanced Contrast (CT-NEC) revealed a gut wall thickness in left hypochondrium and multiple focal calcifications. Contrast enhanced computed tomography (CECT) revealed non-homogenous enhancement with circumferential gut wall thickening and narrowing lumen plus AV malformations in the gut wall giving impression of mass in the jejunum with AV malformation. An exploratory laprotomy was performed. The resected jejunum showed a protruding solid mass. The mass was confirmed to be a spindle cell type GIST and was intermingled with the AVM. To our knowledge, this is the second case of an AVM associated with a GIST. First case was reported in 2008 by Shim SH et al 1.
key words: Gastrointestinal stromal tumor; Arteriovenous malformation; Jejunum.

         

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