Skin Ulceration Due to Metastatic Emboli from Ventricular Myxoma

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

Skin Ulceration Due to Metastatic Emboli from Ventricular Myxoma

Ambreen Moatasim, Anwar Ul Haque and Ayesha Masood
Department of Pathology, Pakistan Institute of Medical Sciences, Islamabad.

We report a case of left ventricular myxoma metastasizing to blood vessels of extremities and causing cutaneous ulceration.
Most of left ventricular myxomas are symptomatic (92.7%). Systemic embolism is the most common manifestation (50%) and
often leads to death.3 The propensity of cardiac myxomas to embolize is thought to be related to tumor morphology, with
friable and gelatinousmyxomas being more likely to embolize than firm and fibrous lesions.26, 27
The current case is rare in the sense that the myxomatous material had metastasized to blood vessels of hands and legs,
causing arterial insufficiency and hence cutaneous ulceration.

         

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