Muhammad Ihtesham Khan and Ahmareen Khalid
Department of Pathology, Shaheed Zulfiqar Ali Bhutto Medical University,
Pakistan Institute of Medical Sciences, Islamabad
Primitive neuroectodermal tumors (PNETs) of brain are childhood tumours which are frequently located in cerebellum. Supratentorial PNETs are uncommon. These tumors are composed of undifferentiated or poorly differentiated cells of neuroectodermal origin, with the capacity for differentiation along neuronal, astrocytic, ependymal, and melanocytic cell lines. PNET with divergent differentiation in frontal lobe of brain is a rare phenomenon. A case of 6 years old female child having PNET with divergent differentiation (ependymal and neuroblastomal differentiation) in frontal lobe of brain is reported.
Key words: Primitive neuroectodermal tumor (PNET), divergent differentiation, frontal lobe of brain.