Occult Hepatitis-B Infection in Volunteer Blood Donors in Different Hospitals of Peshawar, Khyber Pakhtunkhwa

  • Bashir Ahmad Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Khyber Pakhtunkhwa, Pakistan
  • Mehwish Iqbal Centre for Biotechnology and Microbiology, University of Peshawar, Peshawar, Khyber Pakhtunkhwa, Pakistan
  • Sajid Ali Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Khyber Pakhtunkhwa, Pakistan
  • Tariq Mehar Medical B ward, Hayatabad Medical Complex, Peshawar
  • Shumaila Bashir Department of pharmacy, University of Peshawar, Peshawar, Khyber Pakhtunkhwa, Pakistan
  • Nourin Mahmood Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Khyber Pakhtunkhwa, Pakistan
Keywords: HBV (Hepatitis B Virus), KPK (Khyber Pakhtunkhwa), PCR (Polymerase Chain Reaction)

Abstract

Background: Although screening tests are performed in hospitals of Khyber Pakhtunkhwa, but still some tests are being ignored due to that potential infection is being transmitted.

Objective: This study was designed to find out potential HBV infection transmitted through blood transfusion.

Methodology: In this regard, 200 blood samples, negative for both (anti-HCV and HBsAg) were screened for HB core infection through ELISA technique after screening of routine procedures in the blood banks. Anti-HB core Positive samples were then processed for active HBV infection using Real time PCR.

Results: Out of 200 samples, 17 (8.5%) were positive for anti-HB core and about 4 (23.5%) of the subjects had active HBV infection.

Conclusion: It was concluded that HB core infection was present in apparently healthy individuals. Hence this study suggests that anti-HB core test should also be included in routine screening procedures in different hospitals of KPK.

Published
2020-06-24