Histopathological Variants of Jaw Osteosarcoma

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

Histopathological Variants of Jaw Osteosarcoma

Devi Charan Shetty*, Puneet Ahuja*, Aadithya B. Urs** & Rupinder Kaur*
*I.T.S- CDSR, Ghaziabad & **I.T.S Dental College, Greater Noida. India

Osteosarcoma (OS) is a highly malignant bone forming tumor characterized by frankly to subtly anaplastic stromal cells with
evidence of direct formation of osteoid and/or primitive bone by these cells. Incidence is lower in jaws as compared to long
bones (4-13%). They have different biological behaviour but same histopathology. The mean age of occurrence is third to
fourth decade, almost a decade older than that of osteosarcoma of long bones. The most common presenting features are pain
and swelling, with a radiographic presentation of sunburst appearance. The histopathology of osteosarcoma is highly variable,
ranging from the more commonly seen osteoblastic type to the rare variants like myxomatous and telangiectatic types among
others. The histopathological diversities of jaw osteosarcoma are being presented in the following three cases.


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