Ambereen A Imran, Muhammad Eyyaz Khaleel, Sarosh Majeed Salaria*,
Postgraduate Medical Institute, Lahore, * Department of Pathology, AJK Medical College, Muzaffarabad, Azad
Abstract: Giant cell-rich osteosarcoma needs to be differentiated from malignant giant cell tumor as there are
marked differences in prognoses and treatment. There is considerable overlap in signs, symptoms and
histopathological features. We describe here a 16 year old girl who presented with pain and swelling below the
knee joint and underwent an incisional biopsy. In the light of radiological and pathological features a diagnosis of
Giant cell-rich osteosarcoma was made
Key words: Giant cell-rich osteosarcoma, Giant cell tumor, Osteoid, Tbia.