Fine Needle Aspiration Cytology of Pigmented Dermatofibrosarcoma Protuberance (Bednar Tumor) & it’s Pathogenesis

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

Fine Needle Aspiration Cytology of Pigmented Dermatofibrosarcoma Protuberance (Bednar Tumor) & it’s Pathogenesis

Anwar Ul Haque, Hajra Farooq, Maryam Sharif and Sidra Chaudhary

Department of Pathology, Azad Jammu & Kashmir Medical College, Muzaffarabad, Azad Kashmir, Pakistan

 

Abstract: Dermatofibrosarcoma protuberance is a soft tissue tumor of low malignant potential. At times it is associated with pigment deposits which are then it is termed as Bednar tumor. Only a few Fine Needle Aspiration Cytology studies of Bednar Tumor have been reported. We share our findings of Fine Needle Aspiration Cytology in a 30 year old man with Bednar tumor of scalp and multiple enlarged cervical lymph nodes. Our smears revealed scattered atypical large round to oval cells with scant cytoplasm. Some cells’ cytoplasm contained abundant melanin pigment which also resulted in dirty black pigmented background. The tissue sections showed melanin in both spindle shaped cells and rounded cells. At places it seemed that heavily pigmented cells became oval and globular and necrotic. The melanin pigment was extended into the cellular processes. The overlying skin epidermis shows focal kilocytotic type change. The tissue sections showed positivity for CD 34 and protein S-100. We propose that round globular cells are derived from spindly cells after melanin synthesis and when the cytoplasm is overloaded with melanin the cells undergo necrosis. Focal kilocyototic type change in overlying epidermis deserves further investigation.

         

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