Cryptococcal Meningitis ——— Case Report and Review of Literature

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

Cryptococcal Meningitis ——— Case Report and Review of Literature

R. Hafeez*, A.S. Chughtai.
* Consultant Microbiologist, Chughtais Lab, 8, Jail Road, Lahore.
Cryptococcus neoformans is a saprophytic
encapsulated yeast with a worldwide distribution
in soil contaminated usually with avian excreta,
mostly from pigeons(1). Infection is acquired
by inhalation of the organism and could be
asymptomatic and limited to the lungs, especially in
the immunocompetent host.(2) Haematogenous
dissemination, especially to the meninges, and fatal
outcome occurs in patients with other disorders,
particularly malignancy, diabetes mellitus, treatment
with corticosteroids and infection with human
immunodeficiency virus.(3) Although there is a
marked increase in the incidence of cryptococcosis
around the world, due to its association with AIDS,
reports concerning this infection from our region are
Here we report a case of C. neoformans
meningitis and present an update on the pertinent
literature, especially in relation to non AIDS versus
AIDS patients.


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