Basaloid Squamous Cell Carcinoma of the Uterine Cervix

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

Basaloid Squamous Cell Carcinoma of the Uterine Cervix

Ambereen A Imran*, Sarosh Majeed Salaria**
Departments of Pathology, *Postgraduate Medical Institute, Lahore, ** AJK Medical College, Muzaffarabad

Basaloid squamous cell carcinoma (BSCC) is a rare and highly aggressive variant of squamous cell carcinoma. It
was first described by Wain et al in 1986. The characteristic histologic features are nests, groups, trabeculae and
lobules of small basaloid cells with peripheral palisading. There may be areas of comedonecrosis. The tumor has, in
some cases, been found to be associated with areas of typical squamous cell carcinoma. The most frequently
involved sites are larynx, hypopharynx, tonsils and base of tongue. But other areas of the body like nose, paranasal
sinuses, external ear, submandibular region, oesophagus, lung, uterine cervix, vulva, vagina and anus are reported
to be afflicted. A case of BSCC of uterine cervix was encountered and is being reported here.
Key words: Basaloid squamous cell carcinoma, Squamous cell carcinoma, peripheral palisading, basaloid cells


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