An unusual case of dyspepsia

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

An unusual case of dyspepsia

Abdul Khalid and M. Tariq Baqai
Department of Medicine Azad Jammu & Kashmir Medical College, Muzaffarbad, Azad Kashmir, Pakistan

A fifty six years old man presented with post prandial upper abdominal discomfort that gradually worsened over
the last three months. There was history of anorexia and vomiting associated with early satiety and weight loss.
On physical examination, the patient had normal physical examination except that he was pale. Patient’s upper
gastrointestinal endoscopy showed poorly distensible stomach with diffuse nodular growth involving distal part of
body of stomach. The biopsy showed poorly differentiated large cell lymphoma of stomach. Less than 15% gastric
malignancies account for lymphomas. The majority of these tumors are Non-Hodgkin’s lymphomas of B-cell origin.
Patient received chemotherapy (CHOP + Rituximab). Follow up endoscopic biopsies and PET scan at six was
normal with no residual tumor activity.
Keywords: Gastric malignancy, lymphoma, dyspepsia


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