A Revisit to Foetal “Rhabdomyoma”: An Electronmicroscopic and Immunologic Evaluation

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

A Revisit to Foetal “Rhabdomyoma”: An Electronmicroscopic and Immunologic Evaluation

Anwar Ul Haque* and U. M. Chowdhary**
* Head, Department of Pathology, PIMS, Islamabad.
** King Faisal University Dammam Saudi Arabia.
The fetal “rhabdomyoma” is a rare tumor
occurring most commonly in the scalp of young
chidren1. The tumor closely mimics embryonal
rhabdomyosarcoma by light microscopy, however, it
lacks frequent mitoses and persues a benign course.
We examined a case of classical “Fetal
Rhabdomyoma”. In addition to the routine
histopathology, immunoperoxidase and electronmicroscopic
studies were carried out. Our findings
negate the origin of this tumor from skeletal muscle
and support its origin from fibroblast. The presence of
markedly dilated endoplasmic reticulum in fibroblasts
gave a false impression of cross striation on light
microscopy. We propose that the name of this
lesion may be changed from Fetal Rhabdomyoma to
Fetal Fibroma.

         

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