A Revisit to Foetal “Rhabdomyoma”: An Electronmicroscopic and Immunologic Evaluation

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Professor, Consultant Pathologist, American Board Certified Pathologist, Fellow College of American Pathologists. Areas of interest Fine Needle Aspiration Cytology, Cytology, Cancer, Ethics, Islam, Humanity

A Revisit to Foetal “Rhabdomyoma”: An Electronmicroscopic and Immunologic Evaluation

Anwar Ul Haque* and U. M. Chowdhary**
* Head, Department of Pathology, PIMS, Islamabad.
** King Faisal University Dammam Saudi Arabia.
The fetal “rhabdomyoma” is a rare tumor occurring most commonly in the scalp of young chidren1. The tumor closely mimics embryonal rhabdomyosarcoma by light microscopy, however, it lacks frequent mitoses and persues a benign course. We examined a case of classical “Fetal Rhabdomyoma”. In addition to the routine histopathology, immunoperoxidase and electron-microscopic studies were carried out. Our findings negate the origin of this tumor from skeletal muscle and support its origin from fibroblast. The presence of markedly dilated endoplasmic reticulum in fibroblasts gave a false impression of cross striation on light microscopy. We propose that the name of this lesion may be changed from Fetal Rhabdomyoma to Fetal Fibroma.

         

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